Microbicides, vaccines may need to repel HIV contact at mucosa

Source: Aidsmap

HIV can damage the walls of cells in the mucous membranes in the genital tract and the intestines, permitting the virus to pass across these barriers and infect vulnerable cells below, even when the tissue is undamaged, Canadian researchers report this week in the journal PLoS Pathogens.

The findings suggest that microbicides and vaccines may have the greatest chance of success if they can limit or prevent completely contacts between HIV’s gp120 surface protein and cells in the mucous membranes of the genital tract and the intestines.

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